Principles of Evolutionary Medicine is divided into three parts: The first presents a systematic approach to the application of evolutionary principles to human health and disease, using specific examples. This part covers chapters on evolutionary processes, molecular evolution, human evolution, life history theory, and evolutionary developmental biology. The second part presents the application of these principles to our understanding of nutrition, metabolism, reproduction, infectious disease and stress management, and human behavior. The final part provides a general framework for how the principles of evolutionary medicine can be applied in practical terms to the practice of medicine and public health.